Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209005 | 0.77 | KCNJ1 (0.34) | LMNAMAPTPDE4AKCNJ1 | |
| SCHEMBL13045111 | 0.75 | SMN1; SMN2 (0.47) | LMNAMAPT | |
| SCHEMBL20604766 | 0.73 | HDAC8 (0.31) | HDAC8 | |
| SCHEMBL20168441 | 0.72 | KCNJ1 (0.37) | LMNAMAPTPDE4AKCNJ1 | |
| SCHEMBL28835722 | 0.72 | DYRK1A (0.31) | — | |
| SCHEMBL30714963 | 0.72 | PDE4A (0.33) | PDE4A | |
| SCHEMBL21893500 | 0.71 | ALOX5AP (0.38) | LMNAMAPTALOX5AP | |
| SCHEMBL31352427 | 0.71 | HSD11B1 (0.43) | ALOX5AP | |
| SCHEMBL7044640 | 0.71 | HPGD (0.49) | LMNAMAPTMAPK10 | |
| Hydrochloric Acid SCHEMBL29639682 | 0.71 | HSP90AA1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139862-A | It can be used as the bicyclic heterocycles derivative of ROMK channel inhibitor being substituted | 百时美施贵宝公司 | 2019-08-16 | — | — | CN | disclosed |