SCHEMBL7044640

SCHEMBL7044640

Cc1ncn(-c2ccccc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MEN1 O00255 1/20 0.49
ALOX15B O15296 1/20 0.49
KMT2A Q03164 1/20 0.49
SMN1; SMN2 Q16637 5/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
MAPT P10636 8/20 0.45
TP53 P04637 4/20 0.45
LMNA P02545 1/20 0.43
NOTUM Q6P988 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202016 0.84 MAPK8 (0.42) HPGDALDH1A1MEN1ALOX15BKMT2A
SCHEMBL13183810 0.83 ALDH1A1 (0.45) HPGDALDH1A1MEN1ALOX15BKMT2A
SCHEMBL28332943 0.81 MAPK10 (0.43) HPGDALDH1A1MEN1ALOX15BKMT2A
SCHEMBL16202014 0.80 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2MAPT
SCHEMBL719952 0.79 MAPK10 (0.42) HPGDALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL15299233 0.79 MAPK10 (0.42) HPGDALDH1A1MEN1ALOX15BKMT2A
SCHEMBL719104 0.79 MAPT (0.46) MAPTLMNAMAPK10CYP3A4PSEN1
SCHEMBL16202024 0.79 MAPK10 (0.42) HPGDMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL4873943 0.79 MAPK10 (0.42) HPGDALDH1A1MEN1ALOX15BKMT2A
SCHEMBL16202009 0.79 NOTUM (0.46) MEN1KMT2ANPC1RAB9ANOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115819358-B Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2025-02-11 CN claimed
CN-115819358-A Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2023-03-21 CN claimed
CN-115819358-B Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2025-02-11 CN disclosed
CN-115819358-B Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2025-02-11 CN disclosed
CN-115819358-B Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2025-02-11 CN disclosed
CN-117447412-A Process for preparing triazolinones herbicide intermediates 甘肃康巴斯生物科技有限公司 2024-01-26 CN disclosed
US-20230242531-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2023-08-03 US disclosed
CN-116120248-A Preparation method of aryl triazolinone 宁夏格瑞精细化工有限公司 2023-05-16 CN disclosed
US-20230145249-A1 Monoacylglycerol Lipase Modulators JANSSEN PHARMACEUTICA NV (BE) 2023-05-11 US disclosed
CN-115819358-A Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2023-03-21 CN disclosed
CN-115819358-A Method for continuously synthesizing 3-methyl-1-phenyl-1, 2, 4-triazole-5-ketone metal salt 湖南化工研究院有限公司 2023-03-21 CN disclosed
US-6043282-A FUNGICIDES, PESTICIDES, INSECTICIDES, NEMATOCIDES, MITICIDES BASF AKTIENGESELLSCHAFT (DE) 2000-03-28 US disclosed
US-5981581-A FOR CONTROLLING ANIMAL PESTS OR HARMFUL FUNGI BASF AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed
US-5977146-A Pyridylcarbamates, process and intermediates for their preparation, and their use BASF AKTIENGESELLSCHAFT (DE) 1999-11-02 US disclosed
US-5977399-A Iminooxymethyleneanilides, preparation thereof and intermediates therefor, and compositions containing them BASF AKTIENGESELLSCHAFT (DE) 1999-11-02 US disclosed
US-5965587-A PESTICIDES, FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1999-10-12 US disclosed
EP-0888311-A1 PYRIMIDYL PHENYL AND BENZYL ETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1999-01-07 EP disclosed
CN-1192200-A Phenylacetic acid derivatives, process and intermediates for their preparation, and their use as pest-killing compositions and fungicides BASF AG (DE) 1998-09-02 CN disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed
WO-1997033874-A1 PYRIMIDYL PHENYL AND BENZYL ETHERS, PROCESS AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 1997-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242531-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP HPGD 1080/4885ALDH1A1 344/4885MEN1 4127/4885
US-20230145249-A1 Monoacylglycerol Lipase Modulators MGLL, LPL, PNLIP HPGD 1749/4885ALDH1A1 312/4885MEN1 4128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.