Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL757747 | 0.87 | KDM4E (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL8859782 | 0.82 | ALDH1A1 (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL4958710 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL31171419 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL52405 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL29366129 | 0.79 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| Iodide SCHEMBL5967814 | 0.76 | ALDH1A1 (0.94) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL1128021 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL22788818 | 0.73 | KDM4E (0.67) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL18950744 | 0.73 | KDM4E (0.75) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156988-A | A kind of phenanthro- imidazole radicals aerotex and its preparation method and application | 湘潭大学 | 2019-08-23 | — | — | CN | claimed |
| CN-110156988-A | A kind of phenanthro- imidazole radicals aerotex and its preparation method and application | 湘潭大学 | 2019-08-23 | — | — | CN | disclosed |