Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30791368 | 0.85 | ADRB2 (0.45) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL23525696 | 0.85 | ADRB2 (0.45) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL15687192 | 0.81 | GPR84 (0.50) | GPR84HTR6MEN1KMT2AMAPT | |
| SCHEMBL12850750 | 0.80 | GPR84 (0.79) | GPR84HTR2AHTR6MEN1KMT2A | |
| SCHEMBL9400590 | 0.79 | ADRB2 (0.49) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL3320875 | 0.78 | HTR1D (0.68) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL3323916 | 0.76 | ADRB2 (0.50) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL3353042 | 0.75 | HTR6 (0.47) | GPR84HTR2AHTR6ADRB2HTR1D | |
| SCHEMBL15687602 | 0.74 | HASPIN (0.50) | GPR84ALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL10577553 | 0.74 | ADRB2 (0.44) | GPR84HTR2AHTR6ADRB2HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183371-A | A kind of preparation process of zafirlukast intermediate | 南京医科大学 | 2019-08-30 | — | — | CN | disclosed |