Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3107355 | 0.81 | NOTUM (0.40) | CYP1A2KDM4EALOX15HSD17B10ALDH1A1 | |
| SCHEMBL28992453 | 0.76 | KDM4E (0.36) | CYP1A2CYP2C19KDM4EALOX15HSD17B10 | |
| SCHEMBL28452345 | 0.74 | TRPA1 (0.32) | CYP1A2ALDH1A1MAPT | |
| SCHEMBL19914848 | 0.74 | CYP1A2 (0.42) | CYP1A2CYP2C19KDM4EALOX15HSD17B10 | |
| SCHEMBL28315220 | 0.73 | ALDH1A1 (0.48) | CYP1A2CYP2C19KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL31050110 | 0.71 | CYP1A2 (0.46) | CYP1A2CYP2C19KDM4EALOX15HSD17B10 | |
| SCHEMBL7975208 | 0.71 | CYP1A2 (0.46) | CYP1A2CYP2C19KDM4EALOX15HSD17B10 | |
| SCHEMBL11773357 | 0.69 | — | — | |
| SCHEMBL27950382 | 0.69 | POLB (0.48) | KDM4EHSD17B10ALDH1A1HPGDMAPT | |
| SCHEMBL8852021 | 0.69 | TSHR (0.44) | CYP1A2CYP2C19KDM4EALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183392-B | Preparation method of 3-substituted phenyl-4, 5-dihydroisoxazole derivative, application and intermediate thereof | 河北医科大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-110183392-A | A kind of preparation method and its usage and intermediate of 3- substituted-phenyl -4,5- dihydro-isoxazole derivative | 河北医科大学 | 2019-08-30 | — | — | CN | disclosed |