SCHEMBL28314083

SCHEMBL28314083

Nc1ccc(N)c2c1C(=O)c1ccccc1C2=O.Nc1ccc2c(c1)C(=O)c1ccc(N)cc1C2=O.Nc1ccc2c(c1N)C(=O)c1ccccc1C2=O.Nc1cccc2c1C(=O)c1c(N)cccc1C2=O.Nc1cccc2c1C(=O)c1cccc(N)c1C2=O.Nc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.67
MAOB P27338 1/20 0.67
ADORA2A P29274 5/20 0.61
ALDH1A1 P00352 7/20 0.58
MAPK1 P28482 6/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
RAB9A P51151 4/20 0.58
NPC1 O15118 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
CYP3A4 P08684 2/20 0.58
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
CSNK1A1 P48729 2/20 0.53
CSNK1D P48730 2/20 0.53
CSNK1G1 Q9HCP0 2/20 0.53
FGR P09769 1/20 0.53
PIM1 P11309 1/20 0.53
DYRK1A Q13627 1/20 0.53
HIPK2 Q9H2X6 1/20 0.53
MEN1 O00255 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28314104 1.00 MAOA (0.67) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL28314829 0.94 ALDH1A1 (0.63) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL28509366 0.91 MAOA (0.80) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL28314830 0.91 MAOA (0.55) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL4444783 0.88 ADORA2A (0.72) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL29361856 0.88 ADORA2A (0.72) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL8773084 0.88 ADORA2A (0.72) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL30377911 0.88 ADORA2A (0.72) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL487001 0.82 MAOA (1.00) MAOAMAOBADORA2AALDH1A1MAPK1
SCHEMBL30129869 0.82 MAOA (1.00) MAOAMAOBADORA2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110092389-A A kind of tourmaline of surface grafting anthraquinone compounds, preparation method and application 厦门理工学院 2019-08-06 CN disclosed