Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 4/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137885 | 0.73 | TSHR (0.44) | RETALOX15 | |
| Tert-Butyl Formate SCHEMBL27789519 | 0.71 | TDP1 (0.42) | KMT2A | |
| SCHEMBL20069163 | 0.71 | OPRD1 (0.40) | RETALDH1A1KMT2ACETPNOX1 | |
| SCHEMBL28314925 | 0.71 | RET (0.40) | RETALDH1A1NLRP3KMT2ACETP | |
| SCHEMBL20158642 | 0.68 | OPRM1 (0.46) | RETALDH1A1KMT2ACETPCYP2D6 | |
| Tert-Butyl Formate SCHEMBL27814649 | 0.68 | TDP1 (0.48) | — | |
| Tert-Butyl Formate SCHEMBL27789570 | 0.67 | TDP1 (0.41) | KMT2A | |
| Tert-Butyl Formate SCHEMBL28828203 | 0.67 | TDP1 (0.52) | — | |
| SCHEMBL20224882 | 0.67 | CYP1A2 (0.52) | ALDH1A1KHKKMT2ACETPCYP2D6 | |
| SCHEMBL1446943 | 0.67 | LIMK2 (0.53) | KHKUSP2CYP2D6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |