Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137885 | 0.81 | TSHR (0.44) | RET | |
| SCHEMBL20069163 | 0.79 | OPRD1 (0.40) | RETALDH1A1CETPOPRM1OPRD1 | |
| SCHEMBL20158642 | 0.76 | OPRM1 (0.46) | RETALDH1A1CETPOPRM1OPRD1 | |
| SCHEMBL20205744 | 0.74 | OPRM1 (0.44) | RETALDH1A1CETPOPRM1OPRD1 | |
| Tert-Butyl Formate SCHEMBL28314926 | 0.71 | RET (0.35) | RETALDH1A1CETPNLRP3NOX1 | |
| SCHEMBL27796299 | 0.69 | OPRL1 (0.41) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL27789518 | 0.69 | — | — | |
| SCHEMBL27797082 | 0.68 | CHRM3 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL28844207 | 0.68 | RBP4 (0.48) | ALDH1A1 | |
| SCHEMBL23290589 | 0.68 | GPR119 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177786-A | Pyrazolo [1,5-A] pyridine compounds being substituted are as RET kinase inhibitor | 阿雷生物药品公司 | 2019-08-27 | — | — | CN | disclosed |