SCHEMBL28316100

SCHEMBL28316100

O=S(=O)(Cc1nccs1)OC(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.39
CYP2C19 P33261 1/20 0.36
PTGS2 P35354 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.32
PKM P14618 2/20 0.32
ALDH1A1 P00352 1/20 0.32
SLC6A3 Q01959 3/20 0.32
CHRM2 P08172 1/20 0.31
CHRM1 P11229 1/20 0.31
CHRM3 P20309 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 1/20 0.31
HIF1A Q16665 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SCN3A Q9NY46 2/20 0.30
ACP1 P24666 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2376213 0.71 CYP1A2 (0.47) FDPSCYP2C19PTGS2CYP1A2CYP2C9
SCHEMBL2037446 0.71 CYP2C19 (0.45) FDPSCYP2C19CYP1A2CYP2C9PKM
SCHEMBL2376209 0.71 FDPS (0.42) FDPSCYP2C19CYP1A2CYP2C9PKM
SCHEMBL12854153 0.69 CYP2C19 (0.41) FDPSCYP2C19CYP1A2CYP2C9TRPM8
Hydrochloric Acid SCHEMBL28585523 0.69 ACP1 (0.45) FDPSCYP2C19CYP1A2CYP2C9PKM
SCHEMBL3511229 0.68 CYP2C19 (0.40) FDPSCYP2C19CYP1A2CYP2C9PKM
SCHEMBL28464067 0.67 CHRM1 (0.53) FDPSCYP2C19CYP1A2CYP2C9ALDH1A1
SCHEMBL3511886 0.67 FDPS (0.42) FDPSCYP2C19CYP1A2CYP2C9PKM
SCHEMBL1725884 0.66 FDPS (0.40) FDPSCYP2C19PTGS2CYP2C9PKM
SCHEMBL1507848 0.66 PTGS2 (0.38) FDPSCYP2C19PTGS2PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732573-B Halogenated S- (perfluoroalkyl)-dibenzothiophenes salt and preparation method thereof 浙江九洲药业股份有限公司 2019-09-06 CN disclosed