Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797268 | 0.78 | FBP1 (0.38) | SLC40A1ACP1TSHRALDH1A1NOS1 | |
| SCHEMBL20679918 | 0.77 | NAMPT (0.46) | CYP2C19CYP1A2CYP2C9SLC40A1CYP2D6 | |
| SCHEMBL2037446 | 0.76 | CYP2C19 (0.45) | CYP2C19FDPSCYP1A2CYP2C9SLC6A3 | |
| SCHEMBL2376213 | 0.76 | CYP1A2 (0.47) | CYP2C19FDPSCYP1A2CYP2C9SLC6A3 | |
| SCHEMBL2376209 | 0.76 | FDPS (0.42) | CYP2C19FDPSCYP1A2CYP2C9SLC6A3 | |
| SCHEMBL3510928 | 0.75 | ALDH1A1 (0.39) | CYP2C19ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL28585523 | 0.74 | ACP1 (0.45) | CYP2C19FDPSCYP1A2CYP2C9SLC6A3 | |
| SCHEMBL12854153 | 0.74 | CYP2C19 (0.41) | CYP2C19FDPSCYP1A2CYP2C9SLC6A3 | |
| SCHEMBL15689278 | 0.74 | ALDH1A1 (0.53) | CYP2C19CYP1A2CYP2D6ALDH1A1HSD17B10 | |
| SCHEMBL8796833 | 0.74 | NAMPT (0.32) | SLC40A1NAMPTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293919-B2 | Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds | CRESTONE, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20100286169-A1 | Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds | CRESTONE, INC. (US) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286169-A1 | Antibacterial Sulfone and Sulfoxide Substituted Heterocyclic Urea Compounds | TST, UMPS, UROD | CYP2C19 1318/4885FDPS 245/4885CYP1A2 2368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.