Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875688 | 0.70 | DRD2 (0.40) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL22162664 | 0.67 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL13767609 | 0.67 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL28314238 | 0.67 | DRD2 (0.41) | MEN1KMT2AGAACTSKCTSS | |
| SCHEMBL31121749 | 0.66 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL31121751 | 0.66 | CTSK (0.54) | CTSKCTSS | |
| SCHEMBL23168272 | 0.66 | TDP1 (0.59) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL10190369 | 0.66 | TDP1 (0.59) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL8062203 | 0.66 | TDP1 (0.59) | MEN1KMT2AMAPTPOLBGAA | |
| SCHEMBL20358461 | 0.66 | MEN1 (0.56) | MEN1KMT2AMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382942-B | 8- polyamines base dihydromyricetin derivative and its preparation method and application | 石家庄学院 | 2019-07-30 | — | — | CN | disclosed |