Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875688 | 0.97 | DRD2 (0.40) | DRD2MEN1GAAKMT2AMALT1 | |
| SCHEMBL21973378 | 0.72 | MALT1 (0.47) | DRD2MEN1GAAKMT2AMALT1 | |
| SCHEMBL21973377 | 0.72 | MALT1 (0.47) | DRD2MEN1GAAKMT2AMALT1 | |
| SCHEMBL15159962 | 0.71 | CTSK (0.59) | MEN1GAAKMT2AIDO1MMP1 | |
| SCHEMBL15159959 | 0.70 | ATM (0.62) | MEN1GAAKMT2AMMP1MMP3 | |
| SCHEMBL22904156 | 0.70 | IDO1 (0.43) | DRD2MALT1CAMK2DIDO1CDK2 | |
| SCHEMBL21973371 | 0.69 | BRD4 (0.47) | DRD2MEN1GAAKMT2AMALT1 | |
| SCHEMBL6244166 | 0.69 | MEN1 (0.62) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL7730493 | 0.69 | MEN1 (0.62) | MEN1GAAKMT2ACTSKCTSS | |
| SCHEMBL19301024 | 0.69 | MEN1 (0.62) | MEN1GAAKMT2ACTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382942-B | 8- polyamines base dihydromyricetin derivative and its preparation method and application | 石家庄学院 | 2019-07-30 | — | — | CN | disclosed |