Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 5/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363877 | 0.80 | ERBB2 (0.39) | GAAMAPT | |
| SCHEMBL14424028 | 0.79 | KIF11 (0.42) | NOTUMTDP2POLBNISCHTRPV1 | |
| SCHEMBL5223142 | 0.79 | MEN1 (0.53) | L3MBTL1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL9105419 | 0.78 | NOTUM (0.42) | SCN5ANOTUMPOLBL3MBTL1NISCH | |
| Hydrochloric Acid SCHEMBL30879670 | 0.77 | MEN1 (0.51) | L3MBTL1KDM4EGAAMAPTMAPK1 | |
| SCHEMBL3160320 | 0.77 | MAPK14 (0.42) | KDM4EGAA | |
| SCHEMBL6850964 | 0.76 | MEN1 (0.48) | NOTUML3MBTL1KDM4EMAPTMAPK1 | |
| SCHEMBL1160429 | 0.76 | POLB (0.49) | POLBL3MBTL1TRPV1CACNA2D1KDM4E | |
| SCHEMBL15186426 | 0.73 | KDM5B (0.41) | — | |
| SCHEMBL20074712 | 0.73 | NOTUM (0.44) | SCN5ANOTUMPOLBL3MBTL1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191884-A | Substituted 6- (1H-pyrazol-1-yl) pyrimidine-4-amine derivatives and uses thereof | 拜耳公司 | 2019-08-30 | — | — | CN | disclosed |