Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 6/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28318754 | 0.78 | SCN5A (0.45) | NOTUMNISCHSCN10ASCN5ATRPA1 | |
| SCHEMBL9099576 | 0.77 | NOTUM (0.41) | NOTUMNISCHSCN10ASCN5ASCN9A | |
| SCHEMBL28583866 | 0.76 | ALOX15 (0.43) | TRPA1IDO1 | |
| SCHEMBL6588599 | 0.76 | NPC1 (0.55) | KCNH2 | |
| SCHEMBL16201361 | 0.76 | PRMT6 (0.45) | NOTUMNISCHSCN10ASCN5ASCN9A | |
| SCHEMBL16201185 | 0.74 | PRMT6 (0.58) | NOTUMNISCHSCN10ASCN5ASCN9A | |
| SCHEMBL3637301 | 0.74 | MAPT (0.48) | — | |
| SCHEMBL6589442 | 0.74 | NLRP3 (0.61) | — | |
| SCHEMBL16696581 | 0.72 | NOTUM (0.43) | NOTUMNISCHSCN10ASCN5AKCNH2 | |
| SCHEMBL20191087 | 0.71 | SCN5A (0.57) | SCN5ASCN1ASCN2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459571-A1 | NITROIMIDAZOOXAZINES AND THEIR USES IN ANTI-TUBERCULAR THERAPY | Global Alliance For Tb Drug Development (US) | 2012-06-06 | — | — | EP | disclosed |