Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28629254 | 0.84 | KMT2A (0.44) | KMT2ATHRATHRBTDP1ALOX5 | |
| SCHEMBL6293685 | 0.71 | TDP1 (0.50) | KMT2ATHRATHRBTDP1ALOX5 | |
| SCHEMBL29011740 | 0.70 | SLC5A1 (0.59) | KMT2ATHRBTDP1ALOX5ALDH1A1 | |
| SCHEMBL22499185 | 0.70 | TDP1 (0.58) | KMT2ATDP1ALOX5ALDH1A1AKR1C3 | |
| SCHEMBL11527185 | 0.68 | SMN1; SMN2 (0.71) | KMT2ATDP1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL23188350 | 0.68 | KMT2A (0.43) | KMT2ATDP1ALOX5ALDH1A1AKR1C3 | |
| SCHEMBL13978646 | 0.67 | KMT2A (0.66) | KMT2ATDP1ALDH1A1AKR1C3APP | |
| SCHEMBL28439801 | 0.66 | AKR1C3 (0.54) | KMT2ATDP1ALOX5ALDH1A1AKR1C3 | |
| SCHEMBL22528727 | 0.66 | TDP1 (0.53) | KMT2ATDP1ALDH1A1AKR1C3L3MBTL1 | |
| SCHEMBL27744906 | 0.66 | KMT2A (0.56) | KMT2ATDP1ALDH1A1AKR1C3APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256252-B | Acetophenone compound, preparation method and application in preparing medicine for treating cancer | 西北农林科技大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-110256252-A | Acetophenone compounds, preparation method and the application for preparing treating cancer drug | 西北农林科技大学 | 2019-09-20 | — | — | CN | disclosed |