Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28319819 | 0.84 | KMT2A (0.49) | KMT2ATDP1THRATHRBALOX5 | |
| SCHEMBL9175449 | 0.71 | TDP1 (0.54) | KMT2ATDP1AKR1C3ALDH1A1MEN1 | |
| SCHEMBL29011740 | 0.71 | SLC5A1 (0.59) | KMT2ATDP1THRBALOX5AKR1C3 | |
| SCHEMBL7533712 | 0.70 | TDP1 (0.50) | KMT2ATDP1ALOX5L3MBTL1ALDH1A1 | |
| SCHEMBL22499185 | 0.70 | TDP1 (0.58) | KMT2ATDP1ALOX5L3MBTL1AKR1C3 | |
| SCHEMBL11527185 | 0.69 | SMN1; SMN2 (0.71) | KMT2ATDP1L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL13978646 | 0.68 | KMT2A (0.66) | KMT2ATDP1L3MBTL1AKR1C3APP | |
| Phenyl Propionic Acid SCHEMBL9175458 | 0.68 | KEAP1 (0.56) | KMT2ATDP1AKR1C3AKR1C2 | |
| SCHEMBL22528727 | 0.67 | TDP1 (0.53) | KMT2ATDP1L3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL28439801 | 0.67 | AKR1C3 (0.54) | KMT2ATDP1ALOX5AKR1C3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256252-B | Acetophenone compound, preparation method and application in preparing medicine for treating cancer | 西北农林科技大学 | 2021-08-27 | — | — | CN | disclosed |