Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375218 | 0.86 | SLC6A3 (0.68) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL27639137 | 0.83 | KMT2A (0.51) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL10754970 | 0.83 | LMNA (0.53) | SLC6A3KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL30343057 | 0.82 | KDM4E (0.58) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL8699559 | 0.81 | KDM4E (0.73) | ESR1SLC6A3KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL11559171 | 0.81 | KMT2A (0.57) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL2691568 | 0.81 | MAPT (0.51) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL4343990 | 0.81 | KMT2A (0.49) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL7329213 | 0.80 | ESR1 (0.52) | ESR2ESR1SLC6A3KMT2AMAPT | |
| SCHEMBL28320252 | 0.80 | MAPT (0.51) | ESR2ESR1SLC6A3KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883619-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | Choongwae Pharma Corporation (KR) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006126846-A1 | PROCESS OF PREPARATION OF SUBSTITUTED TETRAFLUOROBENZYLANILINE COMPOUND AND ITS PHARMACEUTICALLY APPROVED SALTS | CHOONGWAE PHARMA CORPORATION (KR) | 2006-11-30 | — | — | WO | disclosed |