Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720583 | 0.77 | TSHR (0.50) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7265049 | 0.74 | CYP19A1 (0.44) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10852484 | 0.72 | KIF11 (0.48) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18523028 | 0.72 | KIF11 (0.46) | CYP19A1CYP3A4CYP2C19LMNAMAPT | |
| SCHEMBL12909254 | 0.72 | KIF11 (0.48) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17058061 | 0.72 | KIF11 (0.48) | CYP19A1LMNAMAPTUSP2RAB9A | |
| SCHEMBL14486637 | 0.72 | KIF11 (0.46) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7988271 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28250225 | 0.72 | CYP19A1 (0.43) | CYP19A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1500477 | 0.71 | TSHR (0.58) | CYP1A2CYP2C19MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143963-A | With active pyridazine compound of sterilizing and its preparation method and application | 河南科技大学第一附属医院 | 2019-08-20 | — | — | CN | disclosed |