Phorone

Phorone

SCHEMBL28320285

CC(C)=CC(=O)C=C(C)C.N#CCC#N

nearest known ligand 0.31

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30448778 0.79 MCL1 (0.37) MCL1
Phorone SCHEMBL157728 0.78 LMNA (0.39) ALDH1A1TDP1
Phorone SCHEMBL23856063 0.78 LMNA (0.39) ALDH1A1TDP1
Acetic Acid SCHEMBL16061076 0.75
SCHEMBL6737581 0.75
Phorone SCHEMBL32672539 0.74 LMNA (0.36) ALDH1A1TDP1
Phorone SCHEMBL28899536 0.74 LMNA (0.36) ALDH1A1TDP1
Phorone SCHEMBL30396963 0.74 LMNA (0.36) ALDH1A1TDP1
Phorone SCHEMBL27801489 0.74 LMNA (0.36) ALDH1A1TDP1
Phorone SCHEMBL5084762 0.74 LMNA (0.36) ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110272449-A A kind of malononitrile phorone F-like ion fluorescence probe and its preparation method and application 长江师范学院 2019-09-24 CN claimed
CN-111018773-A Malononitrile phorone zinc ion fluorescent probe and preparation method and application thereof 长江师范学院 2020-04-17 CN disclosed
CN-110272449-A A kind of malononitrile phorone F-like ion fluorescence probe and its preparation method and application 长江师范学院 2019-09-24 CN disclosed
CN-110272449-A A kind of malononitrile phorone F-like ion fluorescence probe and its preparation method and application 长江师范学院 2019-09-24 CN disclosed
CN-110272449-A A kind of malononitrile phorone F-like ion fluorescence probe and its preparation method and application 长江师范学院 2019-09-24 CN disclosed