Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MYOC | Q99972 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722713 | 0.86 | ALDH1A1 (0.50) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL3010141 | 0.82 | TP53 (0.50) | TDP1CES1CES2ALDH1A1LMNA | |
| SCHEMBL11421508 | 0.81 | MAPK1 (0.62) | MEN1KMT2AMAPTRAB9AHTT | |
| SCHEMBL11848197 | 0.81 | MAPT (0.50) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL3751456 | 0.81 | CES1 (0.51) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL26555623 | 0.80 | CA1 (0.50) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL3535210 | 0.80 | MAPT (0.56) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL10344264 | 0.80 | HSPB1 (0.50) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL829966 | 0.79 | LMNA (0.59) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL28577071 | 0.79 | LMNA (0.59) | MEN1KMT2ANPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-111493078-A | Use of piperazinone derivatives, an accelerator and a method for controlling root parasitic weeds | 南开大学 | 2020-08-07 | — | — | CN | disclosed |
| CN-110143932-A | Piperazinone derivs and preparation method thereof, inhibitor and the method for preventing and treating root parasitism weeds | 南开大学 | 2019-08-20 | — | — | CN | disclosed |