SCHEMBL28320660

SCHEMBL28320660

C=Cc1cc(N)cc2c1[nH]c1ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GPR3 P46089 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KIF11 P52732 6/20 0.39
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CDK4 P11802 1/20 0.38
CCND1 P24385 1/20 0.38
PARP1 P09874 1/20 0.38
PIM1 P11309 1/20 0.38
PIM3 Q86V86 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123456 0.81 GABRP (0.43) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL8124176 0.81 KMT2A (0.41) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL8124644 0.81 ABCB1 (0.49) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL8128076 0.81 IDO1 (0.44) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL11315856 0.78 KIF11 (0.50) AHRMEN1MAPTKMT2AALDH1A1
Pavettine SCHEMBL36138 0.78 KIF11 (0.53) AHRMEN1MAPTKMT2AALDH1A1
Pavettine SCHEMBL29450528 0.78 KIF11 (0.53) AHRMEN1MAPTKMT2AALDH1A1
Pavettine SCHEMBL27511814 0.78 KIF11 (0.53) AHRMEN1MAPTKMT2AALDH1A1
SCHEMBL3887451 0.78 POLB (0.51) AHRMEN1MAPTKMT2AALDH1A1
Pavettine SCHEMBL28686824 0.78 KIF11 (0.53) AHRMEN1MAPTKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110257493-A DNA encoding library with the unreadable Encoding oligonucleotides connection of polymerase X-化学有限公司 2019-09-20 CN disclosed