SCHEMBL8124176

SCHEMBL8124176

C=Cc1cc(I)cc2c1[nH]c1ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.41
MEN1 O00255 3/20 0.41
AHR P35869 2/20 0.41
MAPT P10636 2/20 0.41
ALDH1A1 P00352 4/20 0.41
HSD17B10 Q99714 4/20 0.41
GPR3 P46089 2/20 0.41
KIF11 P52732 7/20 0.39
PIM1 P11309 1/20 0.38
PIM3 Q86V86 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8124644 0.81 ABCB1 (0.49) KMT2AMEN1AHRMAPTALDH1A1
SCHEMBL8128076 0.81 IDO1 (0.44) KMT2AMEN1AHRMAPTALDH1A1
SCHEMBL28320660 0.81 AHR (0.41) KMT2AMEN1AHRMAPTALDH1A1
SCHEMBL8123456 0.81 GABRP (0.43) KMT2AMEN1AHRMAPTALDH1A1
SCHEMBL11315856 0.78 KIF11 (0.50) KMT2AMEN1AHRMAPTALDH1A1
Pavettine SCHEMBL29450528 0.78 KIF11 (0.53) KMT2AMEN1AHRMAPTALDH1A1
Pavettine SCHEMBL28686824 0.78 KIF11 (0.53) KMT2AMEN1AHRMAPTALDH1A1
Pavettine SCHEMBL27511814 0.78 KIF11 (0.53) KMT2AMEN1AHRMAPTALDH1A1
Pavettine SCHEMBL36138 0.78 KIF11 (0.53) KMT2AMEN1AHRMAPTALDH1A1
SCHEMBL29938926 0.77 AR (0.43) KMT2AMEN1AHRMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4201441-A A POLYVINYLCARBAZOLE, IODINE COMPOUND, ELUTION CANON KABUSHIKI KAISHA (JP) 1980-05-06 US claimed
EP-0624580-B1 Styrylcoumarin compound, photosensitive resin composition, and hologram recording medium CANON KK (JP) 2000-02-09 EP disclosed
US-5879837-A Styrylcoumarin compound, photosensitive resin composition, and hologram recording medium CANON KABUSHIKI KAISHA (JP) 1999-03-09 US disclosed
EP-0883599-A1 AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1998-12-16 EP disclosed
US-5723633-A Pyran derivative, photosensitive resin composition, and hologram recording medium using it CANON KABUSHIKI KAISHA (JP) 1998-03-03 US disclosed
WO-1997031887-A1 AMINOTETRALIN DERIVATIVES AND COMPOSITIONS AND METHOD OF USE THEREOF ZENECA LIMITED (GB) 1997-09-04 WO disclosed
EP-0329102-B1 Photosensitive material and volume type phase hologram member formed therefrom CANON KK (JP) 1996-05-01 EP disclosed
US-5492942-A Pyran derivative, photosensitive resin composition, and hologram recording medium using it CANON KABUSHIKI KAISHA (JP) 1996-02-20 US disclosed
EP-0369081-B1 Method of preparing volume type hologram film CANON KK (JP) 1996-01-24 EP disclosed
EP-0369444-B1 Photosensitive resin composition and method of preparing volume type phase hologram member using same CANON KK (JP) 1995-06-07 EP disclosed
EP-0627426-A1 Pyran derivative, photosensitive resin composition, and hologram recording medium using it CANON KABUSHIKI KAISHA (JP) 1994-12-07 EP disclosed
EP-0624580-A1 Styrylcoumarin compound, photosensitive resin composition, and hologram recording medium CANON KABUSHIKI KAISHA (JP) 1994-11-17 EP disclosed
EP-0349982-B1 Volume phase type hologram film and photosensitive resin composition employed therefor CANON KK (JP) 1994-10-12 EP disclosed
US-5240795-A Volume phase type hologram film and photosensitive resin composition employed therefor CANON KABUSHIKI KAISHA (JP) 1993-08-31 US disclosed
US-5026618-A Photosensitive material and volume type phase hologram member formed therefrom CANON KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
EP-0369444-A2 Photosensitive resin composition and method of preparing volume type phase hologram member using same CANON KABUSHIKI KAISHA (JP) 1990-05-23 EP disclosed
EP-0369081-A1 Method of preparing volume type hologram film CANON KABUSHIKI KAISHA (JP) 1990-05-23 EP disclosed
EP-0349982-A2 Volume phase type hologram film and photosensitive resin composition employed therefor CANON KABUSHIKI KAISHA (JP) 1990-01-10 EP disclosed
US-4871411-A Method of preparing volume type hologram film CANON KABUSHIKI KAISHA (JP) 1989-10-03 US disclosed
US-4201441-A A POLYVINYLCARBAZOLE, IODINE COMPOUND, ELUTION CANON KABUSHIKI KAISHA (JP) 1980-05-06 US disclosed