Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMO | Q99835 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28537366 | 0.81 | KMO (0.63) | KMOMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL18134297 | 0.81 | KMT2A (0.60) | KMOMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28319645 | 0.81 | KMT2A (0.72) | KMOMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28320796 | 0.81 | KMT2A (0.72) | KMOMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29730468 | 0.80 | KMT2A (0.61) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL21003801 | 0.80 | KMT2A (0.61) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL18731741 | 0.80 | KMT2A (0.61) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL18732403 | 0.80 | KMT2A (0.61) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL190954 | 0.80 | AURKA (0.63) | MAPTKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL29620532 | 0.80 | AURKA (0.63) | MAPTKMT2AMEN1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106496127-B | A kind of preparation method of polysubstituted pyrimidine | 苏州大学 | 2019-09-27 | — | — | CN | disclosed |