Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | ARG1 | P05089 | 2/20 | 0.33 |
| ▸ | ARG2 | P78540 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181629 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11ARG1ARG2ACLY | |
| SCHEMBL525645 | 0.82 | AKR1B1 (0.34) | FFAR1TDP1 | |
| SCHEMBL9183579 | 0.81 | CYP4F2 (0.45) | CYP4F2CYP4A11ARG1ARG2ACLY | |
| SCHEMBL27949090 | 0.81 | ACLY (0.53) | CYP4F2CYP4A11ARG1ARG2ACLY | |
| Bicarbonate SCHEMBL12502157 | 0.80 | AKR1B1 (0.33) | FFAR1TDP1 | |
| SCHEMBL8918324 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11FFAR1TDP1 | |
| SCHEMBL27603862 | 0.79 | — | — | |
| SCHEMBL9177295 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11ARG1ARG2ACLY | |
| SCHEMBL28575669 | 0.78 | ALDH1A1 (0.42) | FFAR1TDP1 | |
| SCHEMBL9185265 | 0.78 | ACLY (0.53) | CYP4F2CYP4A11ARG1ARG2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425654-A | 2, 8-diazaspiro [4.5] decane compounds | 基因泰克公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-115536661-A | Resolution of optically active diazaspiro [4.5] decane derivatives | 奥塔万特科学股份有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-110177790-B | Resolution of optically active diazaspiro [4.5] decane derivatives | 奥塔万特科学股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-110177790-A | Resolution of optically active diazaspiro [4.5] decane derivatives | 奥塔万特科学股份有限公司 | 2019-08-27 | — | — | CN | disclosed |