Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500584 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL525645 | 0.83 | AKR1B1 (0.34) | ALDH1A1MEN1KMT2AAKR1B1GPR84 | |
| Bicarbonate SCHEMBL12502157 | 0.82 | AKR1B1 (0.33) | ALDH1A1MEN1KMT2AAKR1B1GPR84 | |
| SCHEMBL28791891 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL17954033 | 0.79 | GPR84 (0.61) | ALDH1A1MEN1KMT2ACYP1A2AKR1B1 | |
| SCHEMBL27862183 | 0.79 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL28322005 | 0.78 | CYP4F2 (0.37) | TDP1FFAR1 | |
| SCHEMBL27949090 | 0.78 | ACLY (0.53) | CYP1A2PPARGPPARATSHRTDP1 | |
| SCHEMBL3682688 | 0.78 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL276477 | 0.78 | TSHR (0.40) | ALDH1A1MEN1KMT2ACYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112955215-B | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-112955215-A | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2021-06-11 | — | — | CN | disclosed |