Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352791 | 0.76 | KMT2A (0.51) | KMT2APIK3CASMN1; SMN2MTORMAP3K12 | |
| SCHEMBL19686896 | 0.70 | IDH1 (0.42) | KMT2APIK3CASMN1; SMN2MAP3K12MAPT | |
| SCHEMBL20153240 | 0.66 | NAPEPLD (0.33) | PIK3CAMTORHSD17B10PIK3CBPIK3CD | |
| SCHEMBL7675604 | 0.66 | MAPT (0.45) | KMT2ASMN1; SMN2NPSR1MAPTTSHR | |
| SCHEMBL27892245 | 0.66 | KMT2A (0.46) | KMT2ASMN1; SMN2NPSR1MAPTTSHR | |
| SCHEMBL25227992 | 0.65 | PIK3CA (0.48) | PIK3CAMTORPIK3CDPIK3CG | |
| SCHEMBL31730968 | 0.63 | AR (0.34) | PIK3CAMTORHTTLMNAPIK3CG | |
| SCHEMBL31731048 | 0.63 | CNR2 (0.38) | PIK3CASMN1; SMN2MTORHSD17B10PDE10A | |
| SCHEMBL19690992 | 0.62 | NPC1 (0.41) | SMN1; SMN2PDE10A | |
| SCHEMBL8542336 | 0.62 | CASP1 (0.47) | KMT2ASMN1; SMN2MAPK1HRH4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198935-B | Potassium channel modulators | 卡登特治疗公司 | 2022-05-31 | — | — | CN | disclosed |
| CN-110198935-A | Potassium channel modulators | 卡登特治疗公司 | 2019-09-03 | — | — | CN | disclosed |