Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322161 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTMAP4K4L3MBTL1LMNA | |
| Tert-Butyl Formate SCHEMBL28876913 | 0.76 | HTT (0.39) | SMN1; SMN2HTTMAP4K4L3MBTL1NPC1 | |
| SCHEMBL28323179 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTL3MBTL1LMNANPC1 | |
| Tert-Butyl Formate SCHEMBL28322155 | 0.69 | CYP1A2 (0.47) | SMN1; SMN2LMNAMAPTRXFP1TDP1 | |
| SCHEMBL28323174 | 0.68 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTL3MBTL1LMNANPC1 | |
| SCHEMBL28323172 | 0.66 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTMAP4K4L3MBTL1LMNA | |
| SCHEMBL28323182 | 0.66 | ALDH1A1 (0.48) | SMN1; SMN2HTTLMNAALDH1A1KDM4E | |
| SCHEMBL28323196 | 0.65 | HTT (0.42) | SMN1; SMN2HTTMAP4K4NPC1MAPT | |
| SCHEMBL21548891 | 0.63 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTL3MBTL1LMNANPC1 | |
| SCHEMBL23955989 | 0.63 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTLMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198930-A | Pyrimidine derivatives | 第一三共株式会社 | 2019-09-03 | — | — | CN | disclosed |