Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323179 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTIDO1EGFRMAPT | |
| SCHEMBL28323182 | 0.82 | ALDH1A1 (0.48) | SMN1; SMN2HTTIDO1LMNAKDM4E | |
| SCHEMBL28322154 | 0.79 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTEGFRMAPTNPC1 | |
| SCHEMBL28323174 | 0.79 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTIDO1MAPTNPC1 | |
| Tert-Butyl Formate SCHEMBL28876913 | 0.78 | HTT (0.39) | SMN1; SMN2HTTEGFRMAPTNPC1 | |
| SCHEMBL28323172 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTIDO1EGFRMAPT | |
| SCHEMBL21548891 | 0.73 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTIDO1MAPTNPC1 | |
| SCHEMBL21526141 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTMAPTNPC1RAB9A | |
| SCHEMBL28323196 | 0.72 | HTT (0.42) | SMN1; SMN2HTTIDO1MAPTNPC1 | |
| SCHEMBL21548802 | 0.70 | SMN1; SMN2 (0.56) | SMN1; SMN2HTTLMNAKDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198930-A | Pyrimidine derivatives | 第一三共株式会社 | 2019-09-03 | — | — | CN | disclosed |