Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322161 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| SCHEMBL21526074 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| SCHEMBL21548891 | 0.72 | SMN1; SMN2 (0.73) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| SCHEMBL28323179 | 0.72 | SMN1; SMN2 (0.43) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| SCHEMBL28322154 | 0.68 | SMN1; SMN2 (0.39) | SMN1; SMN2HTTLMNARAB9AL3MBTL1 | |
| SCHEMBL23264073 | 0.68 | ALDH1A1 (0.38) | LMNACYP1A2TSHRHPGDALDH1A1 | |
| SCHEMBL28323172 | 0.68 | SMN1; SMN2 (0.44) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| Tert-Butyl Formate SCHEMBL28876913 | 0.67 | HTT (0.39) | SMN1; SMN2HTTRAB9ACYP1A2CYP3A4 | |
| SCHEMBL2097653 | 0.67 | IDO1 (0.65) | SMN1; SMN2HTTLMNARAB9AIDO1 | |
| SCHEMBL21526082 | 0.67 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTLMNARAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198930-A | Pyrimidine derivatives | 第一三共株式会社 | 2019-09-03 | — | — | CN | claimed |
| CN-110198930-A | Pyrimidine derivatives | 第一三共株式会社 | 2019-09-03 | — | — | CN | disclosed |