SCHEMBL28322348

SCHEMBL28322348

O=C(C1c2cc(-c3ccccc3)ccc2-c2ccc(-c3ccccc3)cc21)C1c2cc(-c3ccccc3)ccc2-c2ccc(-c3ccccc3)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MEN1 O00255 1/20 0.44
APAF1 O14727 1/20 0.44
NPC1 O15118 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
XBP1 P17861 1/20 0.44
PTBP1 P26599 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
GALK1 P51570 1/20 0.44
BLM P54132 1/20 0.44
SMAD3 P84022 1/20 0.44
KMT2A Q03164 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
ACMSD Q8TDX5 3/20 0.43
HNF4A P41235 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24444333 0.74 MEN1 (0.44) MAPTSMN1; SMN2MEN1APAF1NPC1
SCHEMBL28220613 0.73 MEN1 (0.44) MAPTSMN1; SMN2MEN1APAF1NPC1
SCHEMBL27831069 0.73 PDK2 (0.47) MAPTSMN1; SMN2MEN1APAF1NPC1
Hydrochloric Acid SCHEMBL3268790 0.72 MEN1 (0.42) MAPTSMN1; SMN2MEN1APAF1NPC1
SCHEMBL25107270 0.72 LMNA (0.42) MAPTSMN1; SMN2MEN1APAF1NPC1
SCHEMBL27558512 0.72 HDAC3 (0.61) MAPTMEN1LMNAHTTKMT2A
SCHEMBL28194168 0.72 DYRK1A (0.48) ALOX5MAOAMAOB
SCHEMBL28831035 0.70 HDAC3 (0.46) MAPTNPSR1
SCHEMBL21879680 0.69 ACMSD (0.68) KMT2AATMACMSDHNF4ADHFR
SCHEMBL20683221 0.69 HTR2A (0.55) MAPTSMN1; SMN2MEN1APAF1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110256456-A The organic nano material and its preparation method and application of thiophene spirane structure glycol racemic modification 南京邮电大学 2019-09-20 CN disclosed