Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12258796 | 0.87 | ACHE (0.59) | ACHEL3MBTL1MAPTKDM4ENQO2 | |
| SCHEMBL20762901 | 0.79 | ACHE (0.50) | ACHEL3MBTL1MAPTKDM4ENPSR1 | |
| SCHEMBL14449460 | 0.79 | ACHE (0.34) | ACHEL3MBTL1MAPTKDM4E | |
| SCHEMBL3146133 | 0.79 | NQO2 (0.44) | MAPTKDM4ENQO2NPSR1LMNA | |
| SCHEMBL23580916 | 0.77 | ALOX5 (0.55) | ACHEMAPTNQO2NPSR1ERN1 | |
| SCHEMBL27180542 | 0.77 | MAP3K14 (0.44) | ACHEL3MBTL1MAPTKDM4ENQO2 | |
| SCHEMBL14125065 | 0.77 | MAPT (0.45) | L3MBTL1MAPTKDM4ENQO2NPSR1 | |
| SCHEMBL15921177 | 0.77 | ACHE (0.43) | ACHEL3MBTL1MAPTKDM4ENQO2 | |
| SCHEMBL156826 | 0.76 | RAPGEF4 (0.45) | ACHEMAPTKDM4ENPSR1LMNA | |
| SCHEMBL16302410 | 0.76 | POLB (0.40) | ACHEL3MBTL1MAPTNQO2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110198928-A | Benzyloxypyridinylcyclopropanecarboxylic acids, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2019-09-03 | — | — | CN | disclosed |