Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 3/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL858 | 0.88 | CYP2D6 (0.42) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| Hydrochloric Acid SCHEMBL10708013 | 0.86 | HTT (0.44) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| Cyclopropane SCHEMBL28325005 | 0.82 | CYP2D6 (0.38) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| Propane SCHEMBL28323919 | 0.80 | HTT (0.49) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL5537752 | 0.77 | IDO1 (0.58) | HTTCYP2D6LMNAADRA1ACYP1A2 | |
| SCHEMBL5536665 | 0.77 | IDO1 (0.45) | SLC6A2SLC6A4SLC6A3KMT2AIDO1 | |
| SCHEMBL27586901 | 0.74 | HTT (0.37) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL7586879 | 0.74 | IDO1 (0.39) | HTTCYP2D6SCN1ASCN2ASCN3A | |
| SCHEMBL27846157 | 0.74 | CYP2D6 (0.38) | CYP2D6LMNATSHRKMT2AKDM4E | |
| SCHEMBL8300706 | 0.73 | HTT (0.46) | HTTCYP2D6SCN1ASCN2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987498-B2 | Enantiomerically pure amines | NABRIVA THERAPEUTICS AG (AT) | 2015-03-24 | — | — | US | disclosed |
| EP-2576531-B1 | Enantiomerically pure amines | NABRIVA THERAPEUTICS AG (AT) | 2014-08-13 | — | — | EP | disclosed |
| EP-2576531-A1 | ENANTIOMERICALLY PURE AMINES | Nabriva Therapeutics AG (AT) | 2013-04-10 | — | — | EP | disclosed |
| US-20130072711-A1 | ENANTIOMERICALLY PURE AMINES | NABRIVA THERAPEUTICS AG (AT) | 2013-03-21 | — | — | US | disclosed |
| WO-2011146953-A1 | ENANTIOMERICALLY PURE AMINES | NABRIVA THERAPEUTICS AG (AT) | 2011-12-01 | — | — | WO | disclosed |
| EP-2390245-A1 | Enantiomerically pure amines | Nabriva Therapeutics AG (AT) | 2011-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072711-A1 | ENANTIOMERICALLY PURE AMINES | PTMA, QPCTL, ATIC | HTT 130/4885CYP2D6 929/4885SCN1A 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.