Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21051142 | 0.79 | NAMPT (0.40) | ALDH1A1LMNA | |
| SCHEMBL7514677 | 0.77 | JMJD6 (0.43) | ALDH1A1GPR119OPRD1OPRK1LMNA | |
| SCHEMBL28485619 | 0.74 | L3MBTL1 (0.43) | ALDH1A1NPSR1LMNA | |
| SCHEMBL3273322 | 0.74 | SMN1; SMN2 (0.33) | ALDH1A1TET2TET1EGLN1HIF1AN | |
| SCHEMBL28740303 | 0.72 | JMJD6 (0.44) | ALDH1A1GPR119OPRD1OPRK1LMNA | |
| SCHEMBL27536831 | 0.72 | HSP90AA1 (0.38) | BRD4GPR119OPRD1OPRK1 | |
| SCHEMBL27797219 | 0.72 | GPR119 (0.34) | ALDH1A1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL31421267 | 0.71 | HSP90AA1 (0.45) | ATRGPR119OPRD1OPRK1LMNA | |
| SCHEMBL3168811 | 0.71 | GPR119 (0.40) | GABRG2GABRB3GPR119OPRD1OPRK1 | |
| SCHEMBL25736840 | 0.71 | GPR119 (0.34) | GPR119OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |