SCHEMBL3273322

SCHEMBL3273322

O=C(O)c1nccn1C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.33
NR4A1 P22736 1/20 0.32
NR4A2 P43354 1/20 0.32
KDM4E B2RXH2 5/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
KDM4A O75164 2/20 0.32
EGLN1 Q9GZT9 2/20 0.32
RAB9A P51151 1/20 0.32
HIF1AN Q9NWT6 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
KDM6B O15054 1/20 0.32
KDM6A O15550 1/20 0.32
TET3 O43151 1/20 0.32
KDM4B O94953 1/20 0.32
KDM5C P41229 1/20 0.32
KDM4D Q6B0I6 1/20 0.32
TET2 Q6N021 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
TET1 Q8NFU7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrazine SCHEMBL27869246 0.94 NAPRT (0.36) SMN1; SMN2KDM4ENAPRTHCAR2ALDH1A1
SCHEMBL8698383 0.87 PARP1 (0.41) SMN1; SMN2NR4A1NR4A2APOBEC3AAPOBEC3G
SCHEMBL27831516 0.86 SMN1; SMN2 (0.33) SMN1; SMN2NR4A1NR4A2KDM4EL3MBTL1
SCHEMBL11846942 0.77
SCHEMBL298299 0.74
SCHEMBL27510365 0.74
SCHEMBL163470 0.74
SCHEMBL28323931 0.74 ALDH1A1 (0.34) EGLN1HIF1ANTET2TET1LMNA
SCHEMBL4342320 0.73
SCHEMBL780236 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019889-B Visible long afterglow-near infrared double-pass fluorescent anti-counterfeiting ink and preparation method thereof 当纳利(成都)印刷有限公司 2025-02-14 CN claimed
CN-117358278-A Monoatomically dispersed Ni-N-C catalyst and preparation method and application thereof 江苏扬农化工集团有限公司 2024-01-09 CN claimed
CN-116404256-B Electrolyte, battery monomer, battery and electric equipment 宁德时代新能源科技股份有限公司 2023-10-27 CN claimed
CN-116364907-B Lithium-rich manganese-based layered cathode material, and preparation method and application thereof 天津巴莫科技有限责任公司 2023-08-29 CN claimed
CN-116404256-A Electrolyte, battery monomer, battery and electric equipment 宁德时代新能源科技股份有限公司 2023-07-07 CN claimed
CN-116364907-A Lithium-rich manganese-based layered cathode material, and preparation method and application thereof 天津巴莫科技有限责任公司 2023-06-30 CN claimed
EP-0000950-A1 Imidazole derivatives and salts thereof and their synthesis THE WELLCOME FOUNDATION LIMITED (GB) 1979-03-07 EP claimed
CN-119019889-B Visible long afterglow-near infrared double-pass fluorescent anti-counterfeiting ink and preparation method thereof 当纳利(成都)印刷有限公司 2025-02-14 CN disclosed
CN-119019889-A Visible long afterglow-near infrared double-pass fluorescent anti-counterfeiting ink and preparation method thereof 当纳利(成都)印刷有限公司 2024-11-26 CN disclosed
US-20240199583-A1 ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS ACHILLION PHARMACEUTICALS, INC. 2024-06-20 US disclosed
US-12006307-B2 Pharmaceutical compounds for treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2024-06-11 US disclosed
US-11926617-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders ACHILLION PHARMACEUTICALS, INC. (US) 2024-03-12 US disclosed
US-20240059702-A1 MACROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2024-02-22 US disclosed
US-4639420-A Method for the immunoanalysis of cholesterol epoxides SCHAFFNER CARL P (US) 1987-01-27 US disclosed
EP-0203968-A1 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES. SCHAFFNER CARL P 1986-12-10 EP disclosed
WO-1986003299-A1 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES SCHAFFNER CARL P 1986-06-05 WO disclosed
EP-0019067-B1 5,10-DIOXO-5,10-DIHYDRODIIMIDAZO(1,5-A,1',5'-D)PYRAZINE-1,6-DICARBOXYLIC ACID AND A PROCESS FOR PRODUCING IMIDAZOLEDICARBOXYLIC ACID AMIDO-DERIVATIVES AJINOMOTO CO., INC. (JP) 1982-10-06 EP disclosed
US-4317830-A ANTISHOCK AGENTS, ANTICOAGULANTS BURROUGHS WELLCOME CO. (US) 1982-03-02 US disclosed
US-4284641-A ANTITHROMBOEMBOLIC AGENT BURROUGHS WELLCOME CO. (US) 1981-08-18 US disclosed
EP-0019067-A1 5,10-Dioxo-5,10-dihydrodiimidazo(1,5-a,1',5'-d)pyrazine-1,6-dicarboxylic acid and a process for producing imidazoledicarboxylic acid amido-derivatives AJINOMOTO CO., INC. (JP) 1980-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12006307-B2 Pharmaceutical compounds for treatment of medical disorders CFD, TFPI, CFH SMN1; SMN2 2329/4885NR4A1 2008/4885NR4A2 3061/4885
US-20240199583-A1 ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF IMMUNE AND INFLAMMATORY DISORDERS CFD, TFPI, CFH SMN1; SMN2 4688/4885NR4A1 552/4885NR4A2 895/4885
US-11926617-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders CFD, TFPI, CFH SMN1; SMN2 4688/4885NR4A1 552/4885NR4A2 895/4885
US-20240059702-A1 MACROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS CFD, TFPI, CFH SMN1; SMN2 2037/4885NR4A1 1597/4885NR4A2 2841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.