Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL1537806 | 0.85 | CALM1 (0.67) | CALM1PLA2G10PLA2G2ALMNALTA4H | |
| Benzyl Alcohol SCHEMBL10856262 | 0.84 | TSHR (0.61) | LTA4HIDH1PPARGPPARACES2 | |
| Ethylbenzene SCHEMBL28174765 | 0.83 | TP53 (0.58) | LMNAPPARGPPARACES2CES1 | |
| Benzyl Alcohol SCHEMBL10862365 | 0.83 | TSHR (0.58) | LTA4HIDH1PPARGPPARACES2 | |
| Benzylamine SCHEMBL283107 | 0.83 | LOXL2 (0.58) | TSHR | |
| (Chloromethyl)Benzene SCHEMBL11339743 | 0.83 | ALDH1A1 (0.39) | LMNACES2CES1AKR1B1MEN1 | |
| Benzyl Alcohol SCHEMBL10863064 | 0.83 | TSHR (0.58) | LTA4HIDH1PPARGPPARACES2 | |
| Benzylamine SCHEMBL11406732 | 0.79 | LOXL2 (0.54) | TSHR | |
| Biphenyl SCHEMBL9009481 | 0.78 | ALDH1A1 (0.47) | LMNABCL2L1MEN1KMT2AHDAC8 | |
| Diphenylmethane SCHEMBL10394702 | 0.77 | CALM1 (0.92) | CALM1PLA2G10PLA2G2ALMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110396096-A | A kind of indoles [3,2-c] coumarin kind compound and its derivative and synthetic method | UNIV EAST CHINA NORMAL | 2019-11-01 | — | — | CN | disclosed |