Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 9/20 | 0.39 |
| ▸ | CA2 | P00918 | 9/20 | 0.39 |
| ▸ | CA12 | O43570 | 6/20 | 0.39 |
| ▸ | CA9 | Q16790 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991813 | 0.85 | HDAC1 (0.36) | MAOAMAOBCA14 | |
| SCHEMBL3488587 | 0.83 | TDP1 (0.38) | TDP1CA14 | |
| SCHEMBL5846398 | 0.82 | CA14 (0.31) | CA14 | |
| SCHEMBL5846385 | 0.82 | CA14 (0.31) | CA14 | |
| SCHEMBL5836122 | 0.81 | CA14 (0.33) | CA14 | |
| SCHEMBL8602376 | 0.81 | CA14 (0.39) | TDP1MAOAMAOBCA14CA1 | |
| SCHEMBL6284923 | 0.80 | CA14 (0.33) | CA14 | |
| SCHEMBL2905983 | 0.80 | HDAC1 (0.33) | CA14 | |
| SCHEMBL5298045 | 0.80 | CA14 (0.31) | CA14 | |
| SCHEMBL15124796 | 0.79 | CTSK (0.39) | MEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164072-B | Monocyclic lactam organic compounds for the treatment of bacterial infections | 诺华股份有限公司 | 2019-10-01 | — | — | CN | disclosed |