Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL991813 | 0.94 | HDAC1 (0.36) | CA14HDAC1HDAC2HDAC6L3MBTL1 | |
| SCHEMBL6284923 | 0.89 | CA14 (0.33) | CA14HDAC1HDAC2HDAC6L3MBTL1 | |
| SCHEMBL5836122 | 0.87 | CA14 (0.33) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL5846398 | 0.86 | CA14 (0.31) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL5846385 | 0.86 | CA14 (0.31) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL2905983 | 0.83 | HDAC1 (0.33) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL28323964 | 0.83 | TDP1 (0.48) | TDP1CA14 | |
| SCHEMBL30772617 | 0.82 | TDP1 (0.49) | TDP1CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL30324862 | 0.82 | TDP1 (0.49) | TDP1CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL3453056 | 0.82 | TDP1 (0.49) | TDP1CA14HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2015-12-17 | — | — | US | disclosed |
| US-9211340-B2 | Means and methods of enhancing delivery to biological systems | CAPSUGEL BELGIUM (BE) | 2015-12-15 | — | — | US | disclosed |
| EP-2561891-A2 | Means and methods of enhancing delivery to biological systems | Botti, Paolo (CH) | 2013-02-27 | — | — | EP | disclosed |
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | CAPSUGEL BELGIUM (BE) | 2010-03-11 | — | — | US | disclosed |
| EP-2068936-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | Botti, Paolo (CH) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008037463-A2 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | BOTTI PAOLO (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062050-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | SGTA, GHRHR, IL36G | TDP1 2906/4885CA14 1527/4885HDAC1 3489/4885 |
| US-20150359899-A1 | MEANS AND METHODS OF ENHANCING DELIVERY TO BIOLOGICAL SYSTEMS | PTMS, HGFAC, SLC43A1 | TDP1 2984/4885CA14 1387/4885HDAC1 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.