Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325457 | 0.79 | SMN1; SMN2 (0.39) | POLBALDH1A1L3MBTL1 | |
| SCHEMBL28325345 | 0.78 | ALDH1A1 (0.38) | POLBALDH1A1 | |
| SCHEMBL14012741 | 0.68 | POLB (0.38) | POLBALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL11892711 | 0.68 | L3MBTL1 (0.36) | POLBCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL12608295 | 0.67 | CNR2 (0.34) | POLBALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL12224198 | 0.67 | L3MBTL1 (0.39) | POLBCHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL11892690 | 0.65 | OPRM1 (0.47) | POLBALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL15134191 | 0.64 | GRM5 (0.36) | POLBALDH1A1TSHRL3MBTL1 | |
| SCHEMBL11892721 | 0.64 | POLB (0.49) | POLBALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL11892718 | 0.63 | L3MBTL1 (0.47) | POLBALDH1A1CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325554-A | Manufacturing method, modified conjugated diene polymer, rubber composition and the tire of modified conjugated diene polymer | 株式会社普利司通 | 2019-10-11 | — | — | CN | disclosed |