SCHEMBL283258

SCHEMBL283258

Oc1ccc(CCN(O)O)cc1O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.61
IGF1R P08069 4/20 0.61
DRD2 P14416 3/20 0.61
DRD1 P21728 3/20 0.61
DRD4 P21917 3/20 0.61
DRD5 P21918 3/20 0.61
DRD3 P35462 3/20 0.61
HIF1A Q16665 3/20 0.61
HSD17B10 Q99714 3/20 0.61
CYP2D6 P10635 2/20 0.61
ADRA1D P25100 2/20 0.61
ADRA1A P35348 2/20 0.61
ADRA1B P35368 2/20 0.61
TSHR P16473 2/20 0.61
NFKB1 P19838 2/20 0.61
CYP3A4 P08684 1/20 0.61
KDM4E B2RXH2 4/20 0.59
PMP22 Q01453 2/20 0.59
MAPT P10636 4/20 0.59
ALDH1A1 P00352 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29648837 1.00 ALOX15 (0.61) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL30631592 0.81 ALOX15 (0.80) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL107956 0.81 ALOX15 (0.80) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL30141595 0.81 HIF1A (0.65) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL10301530 0.81 HIF1A (0.65) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL17044859 0.81 ALOX15 (0.61) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL67764 0.81 HIF1A (0.65) ALOX15IGF1RDRD2DRD1DRD4
Bromide SCHEMBL20854749 0.79 KDM4E (0.66) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL8431254 0.79 ALOX15 (0.76) ALOX15IGF1RDRD2DRD1DRD4
SCHEMBL23309922 0.78 HIF1A (0.77) ALOX15IGF1RDRD2DRD1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250057874-A1 SYNTHETIC MELANIN NANOPARTICLES AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-02-20 US claimed
CN-118946173-A Solar cell module, preparation method thereof and solar cell 江苏汇显显示技术有限公司 2024-11-12 CN claimed
US-12115183-B2 Synthetic melanin nanoparticles and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-10-15 US claimed
US-20220401329-A1 ARTIFICIAL MELANIN NANOPARTICLES AND PRECURSOR MOLECULES AS HAIR DYES NORTHWESTERN UNIVERSITY (US) 2022-12-22 US claimed
WO-2022140532-A2 TOXIN AND GAS ADSORPTION BY POROUS MELANIN NORTHWESTERN UNIVERSITY (US) 2022-06-30 WO claimed
EP-3990423-A2 ARTIFICIAL MELANIN NANOPARTICLES AND METHODS INCLUDING POROUS MELANIN MATERIALS Northwestern University (US) 2022-05-04 EP claimed
CN-113105817-B Side-chain dopamine functionalized polyurethane coating and preparation method and application thereof 华南理工大学 2022-03-25 CN claimed
WO-2021021350-A2 ARTIFICIAL MELANIN NANOPARTICLES AND METHODS INCLUDING POROUS MELANIN MATERIALS NORTHWESTERN UNIVERSITY (US) 2021-02-04 WO claimed
CN-118946173-A Solar cell module, preparation method thereof and solar cell 江苏汇显显示技术有限公司 2024-11-12 CN disclosed
US-20240216892-A1 TOXIN AND GAS ADSORPTION BY POROUS MELANIN NORTHWESTERN UNIVERSITY (US) 2024-07-04 US disclosed
WO-2024107309-A2 HYDROPHOBIC SYNTHETIC MELANIN NANOPARTICLES NORTHWESTERN UNIVERSITY (US) 2024-05-23 WO disclosed
EP-4330220-A1 MELANIN MATERIALS FOR TISSUE REPAIR Northwestern University (US) 2024-03-06 EP disclosed
US-20240000694-A1 Methods and Materials for Matching Chemistry of Individuals and Human Melanin UNIV NORTHWESTERN (US) 2024-01-04 US disclosed
US-20220401329-A1 ARTIFICIAL MELANIN NANOPARTICLES AND PRECURSOR MOLECULES AS HAIR DYES NORTHWESTERN UNIVERSITY (US) 2022-12-22 US disclosed
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2013-09-19 US disclosed
US-20130245269-A1 Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces JUSTUS-LIEBIG-UNIVERSITA GIESSEN (DE) 2013-09-19 US disclosed
WO-2012032084-A1 SYNTHESIS OF TRIPODAL CATECHOL DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2012-03-15 WO disclosed
WO-2012032085-A1 SYNTHESIS OF TRIVALENT FLEXIBLE FRAMEWORKS WITH LIGANDS COMPRISING CATECHOL UNITS FOR FUNCTIONALIZING SURFACES JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) 2012-03-15 WO disclosed
EP-2428503-A1 Synthesis of tripodal catechol derivatives with a flexible base for functionalising surfaces Justus-Liebig-Universität Gießen (DE) 2012-03-14 EP disclosed
EP-2428502-A1 Synthesis of tripodal catechol derivatives with an adamantyl base for functionalising surfaces Justus-Liebig-Universität Gießen (DE) 2012-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245270-A1 Synthesis of Trivalent Flexible Frameworks with Ligands Comprising Catechol Units for Functionalizing Surfaces CHRM3, CHRM5, CHRM4 ALOX15 2851/4885IGF1R 1163/4885DRD2 375/4885
US-20130245269-A1 Synthesis of Tripodal Catechol Derivatives Having an Adamantyl Basic Framework for Functionalizing Surfaces CHRM1, CHRM5, CHRM4 ALOX15 1768/4885IGF1R 1689/4885DRD2 160/4885
US-20220401329-A1 ARTIFICIAL MELANIN NANOPARTICLES AND PRECURSOR MOLECULES AS HAIR DYES TYR, MC1R, TH ALOX15 2812/4885IGF1R 4823/4885DRD2 1675/4885
US-20240000694-A1 Methods and Materials for Matching Chemistry of Individuals and Human Melanin TYR, MC1R, HLA-C ALOX15 2263/4885IGF1R 4792/4885DRD2 1208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.