Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15733013 | 0.82 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTPKMCYP2A13 | |
| SCHEMBL1491068 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTPKMCYP2A13 | |
| SCHEMBL3605369 | 0.79 | GRM2 (0.49) | ALDH1A1L3MBTL1MAPTPKMCYP2A13 | |
| SCHEMBL28866154 | 0.79 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1MAPTPKMCYP2A13 | |
| SCHEMBL1710859 | 0.75 | MEN1 (0.56) | ALDH1A1L3MBTL1MAPTPKMMEN1 | |
| SCHEMBL1628296 | 0.74 | P2RX7 (0.50) | ALDH1A1PKMGRM2HPGDTSHR | |
| SCHEMBL18899216 | 0.71 | GUCY1B2 (0.49) | MEN1KMT2APOLBKDM4ECYP1A2 | |
| SCHEMBL4673966 | 0.70 | KMT2A (0.40) | ALDH1A1PKMMEN1KMT2ALMNA | |
| Pyrrole SCHEMBL13725855 | 0.69 | MEN1 (0.50) | ALDH1A1L3MBTL1MAPTPKMMEN1 | |
| SCHEMBL16796425 | 0.69 | P2RY14 (0.58) | ALDH1A1PKMMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107223125-B | SGC stimulant | 赛科理音医疗有限公司 | 2019-09-27 | — | — | CN | disclosed |