Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CA9 | Q16790 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28326326 | 0.98 | HTT (0.66) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL866410 | 0.91 | CA1 (0.71) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL28087812 | 0.83 | HTT (0.60) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL11041999 | 0.82 | HTT (0.59) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL14594621 | 0.81 | HTT (0.62) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL28363779 | 0.80 | CA1 (0.62) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL7527679 | 0.80 | CA1 (0.62) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL457863 | 0.79 | HSPB1 (0.68) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL10465146 | 0.78 | HTT (0.88) | HTTCA2CA9CA1ALDH1A1 | |
| SCHEMBL18045525 | 0.78 | HTT (1.00) | HTTCA2CA9CA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110408233-A | A kind of p-sulfonic acid benzene oxygen cyanine dyes and preparation method thereof and purposes | UNIV BEIJING | 2019-11-05 | — | — | CN | disclosed |