SCHEMBL7527679

SCHEMBL7527679

O=[N+]([O-])c1ccc(OS(=O)(=O)OCl)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.62
CA2 P00918 8/20 0.62
CA9 Q16790 6/20 0.62
HTT P42858 1/20 0.53
CA12 O43570 5/20 0.48
HSPB1 P04792 1/20 0.46
CA7 P43166 3/20 0.46
ALDH1A1 P00352 3/20 0.46
CA14 Q9ULX7 3/20 0.46
CA3 P07451 2/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA5A P35218 2/20 0.46
CA13 Q8N1Q1 2/20 0.46
CA5B Q9Y2D0 2/20 0.46
HSP90AA1 P07900 1/20 0.46
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
F2 P00734 1/20 0.42
PRSS1 P07477 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL866410 0.88 CA1 (0.71) CA1CA2CA9HTTCA12
SCHEMBL28326326 0.81 HTT (0.66) CA1CA2CA9HTTCA12
SCHEMBL28363779 0.81 CA1 (0.62) CA1CA2CA9HTTCA12
SCHEMBL4826239 0.81 CA1 (0.67) CA1CA2CA9HTTCA12
SCHEMBL28326328 0.80 HTT (0.64) CA1CA2CA9HTTCA12
SCHEMBL8690274 0.77 CA1 (0.67) CA1CA2CA9HTTCA12
Potassium Ion SCHEMBL1902294 0.77 CA1 (0.67) CA1CA2CA9HTTCA12
SCHEMBL866411 0.77 CA1 (0.67) CA1CA2CA9HTTCA12
SCHEMBL31634023 0.77 CA1 (0.67) CA1CA2CA9HTTCA12
SCHEMBL11704991 0.77 CA1 (0.67) CA1CA2CA9HTTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4211146-B1 SYNTHETIC CYCLIC PEPTIDE MIMETICS UNIV BAR ILAN (IL) 2026-05-20 EP disclosed
US-12616760-B2 Synthetic cyclic peptide mimetics BAR ILAN UNIVERSITY (IL) 2026-05-05 US disclosed
EP-4702010-A1 PHOTOACTIVE COMPOUNDS Merck Patent GmbH (DE) 2026-03-04 EP disclosed
CN-114751950-B Cyclic dinucleotide compounds and methods of use 免疫传感器公司 2025-04-18 CN disclosed
WO-2024223739-A1 PHOTOACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2024-10-31 WO disclosed
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS BAR ILAN UNIVERSITY (IL) 2024-09-26 US disclosed
US-11879021-B2 Cyclic peptides and uses thereof Université de Montréal 2024-01-23 US disclosed
US-20230287034-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS JANSSEN BIOTECH INC (US) 2023-09-14 US disclosed
EP-4211146-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS Bar Ilan University (IL) 2023-07-19 EP disclosed
US-11597746-B2 Cyclic dinucleotides as sting agonists JANSSEN BIOTECH, INC. (US) 2023-03-07 US disclosed
EP-3475293-A1 NOVEL CYCLIC PEPTIDES AND USES THEREOF Valorisation-Recherche, Limited Partnership (CA) 2019-05-01 EP disclosed
EP-3429596-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE Immune Sensor, LLC (US) 2019-01-23 EP disclosed
CN-108727249-A The synthetic method of 3- difluoromethyls piperidine hydrochlorate and its derivative 台州学院 2018-11-02 CN disclosed
WO-2018000079-A1 NOVEL CYCLIC PEPTIDES AND USES THEREOF VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) 2018-01-04 WO disclosed
WO-2017161349-A1 CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE IMMUNE SENSOR, LLC (US) 2017-09-21 WO disclosed
WO-2016029324-A1 AZASULFURYLPEPTIDE-BASED CD36 MODULATORS AND USES THEREOF RSEM, LIMITED PARTNERSHIP (CA) 2016-03-03 WO disclosed
EP-0772618-B1 REGIOSELECTIVE SULFATION GENZYME LTD (GB) 2002-04-03 EP disclosed
US-5874548-A SELECTIVELY SULFATED MONO-, DI- AND OLIGOSACCHARIDES, AND THEIR CONJUGATES WHICH ARE INVOLVED IN DIVERSE BIOLOGICAL PROCESSES; PRODUCED EFFICIENTLY WITH LESS PROTECTING/DEPROTECTING STEPS GENZYME CORPORATION (US) 1999-02-23 US disclosed
US-4150223-A ANTIBIOTICS MERCK & CO., INC. (US) 1979-04-17 US disclosed
US-4032521-A ANTIBIOTICS MERCK & CO., INC. (US) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11879021-B2 Cyclic peptides and uses thereof GHRHR, GHSR, GIPR CA1 4293/4885CA2 3674/4885CA9 3349/4885
US-12616760-B2 Synthetic cyclic peptide mimetics TPX2, IAPP, HAX1 CA1 208/4885CA2 2097/4885CA9 792/4885
US-20230287034-A1 CYCLIC DINUCLEOTIDES AS STING AGONISTS STING1, CGAS, IFNAR1 CA1 4807/4885CA2 4072/4885CA9 4739/4885
US-20240316225-A1 SYNTHETIC CYCLIC PEPTIDE MIMETICS IAPP, QPCTL, DNPEP CA1 304/4885CA2 3035/4885CA9 722/4885
US-11597746-B2 Cyclic dinucleotides as sting agonists STING1, CGAS, IFNAR1 CA1 4809/4885CA2 4118/4885CA9 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.