Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.43 |
| ▸ | PRKACA | P17612 | 4/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 4/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 3/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CLK2 | P49760 | 3/20 | 0.43 |
| ▸ | PRKX | P51817 | 3/20 | 0.43 |
| ▸ | JAK3 | P52333 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | MAP4K2 | Q12851 | 3/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327761 | 0.85 | MAPK14 (0.50) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28326474 | 0.85 | CDC7 (0.44) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28327749 | 0.83 | CYP19A1 (0.44) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28326477 | 0.81 | CDC7 (0.47) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28326472 | 0.78 | DHODH (0.42) | ADORA2ADHODHDPP4 | |
| SCHEMBL28327753 | 0.77 | TAAR1 (0.47) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28326488 | 0.77 | CYP19A1 (0.43) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28327746 | 0.74 | CYP2E1 (0.43) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28327764 | 0.72 | IDO1 (0.44) | CDC7MAP4K4PRKACACDK2GSK3B | |
| SCHEMBL28326484 | 0.72 | ALDH1A1 (0.46) | CDC7MAP4K4PRKACACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110423239-A | 1,3- oxazines and 1,2,3- triazole derivative and its synthetic method and application | UNIV KUNMING SCIENCE & TECHNOLOGY | 2019-11-08 | — | — | CN | disclosed |