Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28327764 | 0.83 | IDO1 (0.44) | ALDH1A1SMN1; SMN2DPP4PTK2ADORA2A | |
| SCHEMBL28326474 | 0.80 | CDC7 (0.44) | — | |
| SCHEMBL28326472 | 0.80 | DHODH (0.42) | DHODHDPP4ADORA2AADORA1 | |
| SCHEMBL28326484 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HPGD | |
| SCHEMBL28327750 | 0.78 | DPP4 (0.51) | DHODHDPP4 | |
| SCHEMBL28327761 | 0.75 | MAPK14 (0.50) | — | |
| SCHEMBL28326488 | 0.72 | CYP19A1 (0.43) | ALDH1A1 | |
| Methyl Alcohol SCHEMBL28372647 | 0.71 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL30136447 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 | |
| SCHEMBL294721 | 0.71 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110423239-A | 1,3- oxazines and 1,2,3- triazole derivative and its synthetic method and application | UNIV KUNMING SCIENCE & TECHNOLOGY | 2019-11-08 | — | — | CN | disclosed |