Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576265 | 0.79 | HCAR2 (0.42) | HCAR2ALDH1A1APOBEC3AAPOBEC3GBCL2 | |
| SCHEMBL3577067 | 0.78 | MARS1 (0.45) | HCAR2ALDH1A1APOBEC3AAPOBEC3GKDM4E | |
| SCHEMBL18724843 | 0.75 | HCAR2 (0.39) | HCAR2ALDH1A1BCL2MDM2MCL1 | |
| SCHEMBL12321704 | 0.75 | ALDH1A1 (0.40) | HCAR2ALDH1A1APOBEC3AAPOBEC3GBCL2 | |
| SCHEMBL20064821 | 0.74 | HCAR2 (0.35) | HCAR2ALDH1A1APOBEC3AAPOBEC3GMCL1 | |
| SCHEMBL20461114 | 0.73 | CNR1 (0.45) | HCAR2HCAR3PTGER1 | |
| SCHEMBL6442036 | 0.69 | HCAR2 (0.45) | HCAR2ALDH1A1APOBEC3AKDM4EHCAR3 | |
| SCHEMBL3094695 | 0.68 | P2RY14 (0.55) | P2RY14 | |
| SCHEMBL8508062 | 0.68 | HCAR2 (0.39) | HCAR2ALDH1A1APOBEC3AAPOBEC3GKDM4E | |
| SCHEMBL28252118 | 0.68 | HCAR2 (0.44) | HCAR2ALDH1A1KDM4EHCAR3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106255688-B | Morpholine-pyridine derivate | 豪夫迈·罗氏有限公司 | 2019-11-08 | — | — | CN | disclosed |