Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28760965 | 0.81 | CYP2D6 (0.43) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9294538 | 0.80 | CHRNB2 (0.53) | MEN1KMT2APOLBLMNAHTT | |
| SCHEMBL9294533 | 0.80 | CHRNB2 (0.53) | MEN1KMT2APOLBLMNAHTT | |
| SCHEMBL9294528 | 0.80 | CHRNB2 (0.53) | MEN1KMT2APOLBLMNAHTT | |
| SCHEMBL10685501 | 0.74 | LMNA (0.58) | MEN1KMT2APOLBLMNAHTT | |
| SCHEMBL23117711 | 0.73 | KDM1A (0.42) | MEN1KMT2APOLB | |
| SCHEMBL13525555 | 0.73 | MEN1 (0.64) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL13525552 | 0.73 | MEN1 (0.64) | MEN1KMT2AALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL26134488 | 0.72 | SLC6A2 (0.44) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22492017 | 0.71 | KMT2A (0.67) | MEN1KMT2APOLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177783-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2019-08-27 | — | — | CN | claimed |
| CN-110177783-A | Hormone receptor modulators for the treatment of metabolic conditions and disorders | 阿德利克斯股份有限公司 | 2019-08-27 | — | — | CN | disclosed |