Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.40 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099356 | 0.88 | GABRP (0.41) | AKR1B1FFAR1FFAR4ENPEP | |
| SCHEMBL28247827 | 0.86 | FAAH (0.33) | MEN1KMT2AHSD17B10 | |
| SCHEMBL7025129 | 0.83 | AKR1B1 (0.44) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL9624831 | 0.78 | AKR1B1 (0.45) | AKR1B1GPR84PPARGPPARDPPARA | |
| Bicarbonate SCHEMBL10346411 | 0.78 | MAPT (0.50) | GPR84PPARDFFAR1FFAR4MEN1 | |
| SCHEMBL28791855 | 0.77 | AKR1B1 (0.39) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL27739801 | 0.76 | FFAR4 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL10346410 | 0.76 | FFAR4 (0.53) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL8421581 | 0.75 | LMNA (0.42) | AKR1B1GPR84PPARGPPARDPPARA | |
| SCHEMBL7818137 | 0.74 | AKR1B1 (0.41) | AKR1B1GPR84PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110431142-A | Alicyclic substituted pyrazolo [1,5-a] pyrimidine derivatives of pharmacological activity | RICHTER GEDEON NYRT | 2019-11-08 | — | — | CN | disclosed |