SCHEMBL28818

SCHEMBL28818

O=[N+]([O-])c1cc[nH]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28124895 0.98
SCHEMBL21359713 0.88 ALDH1A1 (0.38)
Pyridine SCHEMBL28328352 0.84 LMNA (0.42)
Morpholine SCHEMBL28750813 0.82 ADRB1 (0.42)
SCHEMBL28131588 0.82 CA1 (0.45)
SCHEMBL4262671 0.81 CA12 (0.48)
SCHEMBL29395816 0.76
SCHEMBL28912911 0.72 CA2 (0.48)
SCHEMBL9567558 0.72 APP (0.56)
SCHEMBL9567561 0.72 APP (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11283 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-12624387-B2 Method for reducing primer dimer formation and increasing amplification efficiency SEEGENE, INC. (KR) 2026-05-12 US claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US claimed
EP-4703360-A1 INTERMEDIATE FOR PREPARING OLIGONUCLEOTIDE ANALOG OR SALT THEREOF, AND PREPARATION METHOD THEREFOR Shanghai Senhui Medicine Co., Ltd. (CN) 2026-03-04 EP claimed
US-12371736-B2 TD probe and its uses SEEGENE, INC. (KR) 2025-07-29 US claimed
US-12338486-B2 Single-stranded break detection in double-stranded DNA MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-06-24 US claimed
CN-114164305-B Primer and parting probe combination for detecting human papilloma virus and application thereof 广州安必平医药科技股份有限公司 2025-03-11 CN claimed
US-20250003011-A1 SAMPLE PREPARATION METHODS USING MODIFIED BASES FOR RAPID IDENTIFICATION AND SEQUENCING DEPIXUS (FR) 2025-01-02 US claimed
EP-4481057-A1 SAMPLE PREPARATION METHODS USING MODIFIED BASES FOR RAPID IDENTIFICATION AND SEQUENCING Depixus (FR) 2024-12-25 EP claimed
CN-117813383-B SiRNA for inhibiting CIDEB gene expression, medicine and application thereof 广州必贝特医药股份有限公司 2024-11-29 CN claimed
US-5908745-A EXCLUSION OF POLYMERIC BEADS, ENZYMES, SURFACTANTS AND HYDROGEN PEROXIDE TO REDUCE LIKELINESS OF DAMAGE TO CONTACT LENSES OR EYES UNIVERSITY OF CHICAGO (US) 1999-06-01 US claimed
WO-1998040518-A9 NUCLEIC ACID INDEXING 1999-02-25 WO claimed
US-5851772-A Microchip method for the enrichment of specific DNA sequences UNIVERSITY OF CHICAGO (US) 1998-12-22 US claimed
WO-1998040518-A2 NUCLEIC ACID INDEXING WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-09-17 WO claimed
EP-0837950-A1 PRIMER WALKING CYCLE SEQUENCING Amersham Life Science (GB) 1998-04-29 EP claimed
EP-0754765-A2 DNA sequencing and DNA terminators LI-COR, INC. (US) 1997-01-22 EP claimed
WO-1997001645-A1 PRIMER WALKING CYCLE SEQUENCING AMERSHAM LIFE SCIENCE (GB) 1997-01-16 WO claimed
EP-0742287-A2 Modified nucleic acid probes McGall, Glenn H. (US) 1996-11-13 EP claimed
US-4962198-A Process for the hydroxylation of electrophilic aromatic compounds BAYER AKTIENGESELLSCHAFT (DE) 1990-10-09 US claimed
US-4300962-A Ammonium nitrate explosive systems THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1981-11-17 US claimed