Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463653 | 0.91 | P2RX4 (0.39) | P2RX4BCHEHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11579499 | 0.83 | P2RX4 (0.37) | P2RX4BCHEALDH1A1TSHRKMT2A | |
| SCHEMBL28317198 | 0.75 | TSHR (0.34) | TSHR | |
| SCHEMBL9546782 | 0.75 | BRD4 (0.37) | HPGDALDH1A1SMN1; SMN2HTTTSHR | |
| SCHEMBL5573133 | 0.74 | ALDH1A1 (0.44) | BCHEALDH1A1SMN1; SMN2HTTTSHR | |
| Ethylene Glycol SCHEMBL29111203 | 0.73 | CA12 (0.33) | ALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL14363762 | 0.72 | GLA (0.31) | — | |
| SCHEMBL19450052 | 0.71 | GLA (0.30) | — | |
| SCHEMBL383890 | 0.70 | GLA (0.31) | — | |
| SCHEMBL23733088 | 0.70 | BRD4 (0.33) | HPGDALDH1A1SMN1; SMN2HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106117340-B | Tumor necrosis factor β analog, its conjugate and its medical usage | 岳阳新华达制药有限公司 | 2019-10-25 | — | — | CN | disclosed |