Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5573133 | 0.78 | ALDH1A1 (0.44) | TSHRLMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL463653 | 0.78 | P2RX4 (0.39) | BRD4TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21582363 | 0.75 | BRD4 (0.35) | BRD4TSHRL3MBTL1LMNAALDH1A1 | |
| Ethylene Glycol SCHEMBL28328461 | 0.75 | P2RX4 (0.35) | BRD4TSHRLMNAALDH1A1HPGD | |
| SCHEMBL18485434 | 0.73 | ALDH1A1 (0.39) | TSHRLMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL22729318 | 0.72 | TSHR (0.50) | BRD4TSHRL3MBTL1LMNAALDH1A1 | |
| SCHEMBL11424950 | 0.71 | BCHE (0.40) | BRD4TSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28317198 | 0.71 | TSHR (0.34) | TSHR | |
| SCHEMBL10603308 | 0.70 | BCHE (0.49) | TSHRL3MBTL1LMNAALDH1A1HPGD | |
| SCHEMBL11579499 | 0.70 | P2RX4 (0.37) | BRD4TSHRL3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993023373-A1 | N-[N'-(5-AMINO-4-HYDROXY-ACYLOYL)-α-AMINOACYLOYL] SUBSTITUTED HETEROCYCLES AND THEIR USE AS ANTIVIRAL AGENTS | PFIZER LIMITED (GB) | 1993-11-25 | — | — | WO | disclosed |